hrp0086p2-p705 | Endocrinology and Multisystemic Diseases P2 | ESPE2016

Endocrinological Disorders in Children with Neurofibromatosis Type 1 and Optic Pathway Gliomas

Nacca Raffaella , Scillipoti Martina , Grandone Anna , Santoro Claudia , Cinalli Giuseppe , Cirillo Mario , Cioffi Daniela , Luongo Caterina , Del Giudice Emanuele Miraglia , Perrotta Silverio , Perrone Laura

Background: Children with neurofibromatosis type 1 (NF1) have an increased risk of developing optic pathway gliomas (OPGs) during childhood. Although these tumors usually have a benign course, some cases result in significant clinical symptoms, including endocrinological disorders.Objective and hypotheses: The aim of this study is to evaluate the endocrinological complications of OPGs involving the chiasm in children with NF1.Metho...